Results of Minimal Dosage Propranolol in the Management of Infantile Haemangioma
Iraqi Postgratuate Medical Journal,
2019, Volume 18, Issue 1, Pages 10-17
Infantile haemangioma one of the most common tumour of new borns , a safe and effective treatment
options are under ongoing research .
The authors show the effectiveness and safety of low dose propranolol as a method for infantile
haemangioma treatment .
In this study twenty- four patients with infantile haemangioma in different anatomical locations were
treated with oral propranolol and the result were assessed in a retrospective analysis of the results
patients were kept on 0.25 mg/kg/day for one month , then on 0.5mg/kg/day in 2 divided doses for
another one month , in the third month the dose will be increased to 1 mg/kg/day in 2 divided doses ,
then the propranolol were given in a maintenance dose ranging between 1-1.5 mg/kg/day in 2 divided
doses according to the clinical response .The duration of treatment ranging from 6-18 months as a
small dose increasing over a long time .
We had achieved excellent result in most of our patients, with reduction of size and fade of color of
hemangioma within 1 month from the initiation of treatment, when we stop the treatment no relapses
were noticed during our follow up period after finishing the course.
Propranolol is one of the safest and most effective treatment options for the infantile haemangioma
even in low dose, with lower relapse rates and minimal consecutive side effects and drawbacks.
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